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Research Article

Neural Stem/Progenitor Cells from the Adult Human Spinal Cord Are Multipotent and Self-Renewing and Differentiate after Transplantation

  • Andrea J. Mothe mail,

    amothe@uhnres.utoronto.ca

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Tasneem Zahir,

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Carlo Santaguida,

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Douglas Cook,

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Charles H. Tator

    Affiliation: Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

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  • Published: November 02, 2011
  • DOI: 10.1371/journal.pone.0027079

About the Authors

Andrea J. Mothe, Tasneem Zahir, Carlo Santaguida, Douglas Cook, Charles H. Tator
Division of Genetics and Development, Toronto Western Research Institute and Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Ontario, Canada

Corresponding Author

Email: amothe@uhnres.utoronto.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AM TZ CT. Performed the experiments: AM. Analyzed the data: AM TZ CT. Contributed reagents/materials/analysis tools: CS DC CT. Wrote the paper: AM CT.