About the Authors
- Bettina Platt
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* E-mail: b.platt@abdn.ac.uk
Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Benjamin Drever
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- David Koss
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Sandra Stoppelkamp
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Amar Jyoti
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Andrea Plano
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Aneli Utan
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Georgina Merrick
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Duncan Ryan
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Valeria Melis
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Hong Wan
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Affiliation Translational & Molecular Medicine, Pfizer BioTherapeutics, Collegeville, Pennsylvania, United States of America
- Marco Mingarelli
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Emanuele Porcu
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Louise Scrocchi
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Affiliation Amorfix Life Sciences, Mississauga, Ontario, Canada
- Andy Welch
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Gernot Riedel
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Affiliation School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
Competing Interests
The authors have read the journal's policy and report the following conflicts: a patent has been submitted on the PLB1 knock-in mouse (US 12/833474). HW is an employee of Pfizer BioTherapeutics, LS is an employee of Amofrix Life Sciences. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Analyzed the data: BP GR BD DR AJ VM GM AP AW. Wrote the paper: BP GR. Designed all experiments and conducted the final data analyses: BP GR. Contributed to the study design: HW. In vitro electrophysiology: BD. Tissue analyses, genotyping and histology: DK SS. Behaviour: DR EP GM AU VM. EEG/activity: AJ AP. PET imaging: AW MM. Amyloid assay: LS.