About the Authors
- Bettina Platt, Benjamin Drever, David Koss, Sandra Stoppelkamp, Amar Jyoti, Andrea Plano, Aneli Utan, Georgina Merrick, Duncan Ryan, Valeria Melis, Marco Mingarelli, Emanuele Porcu, Andy Welch, Gernot Riedel
- School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, United Kingdom
- Hong Wan
- Translational & Molecular Medicine, Pfizer BioTherapeutics, Collegeville, Pennsylvania, United States of America
- Louise Scrocchi
- Amorfix Life Sciences, Mississauga, Ontario, Canada
The authors have read the journal's policy and report the following conflicts: a patent has been submitted on the PLB1 knock-in mouse (US 12/833474). HW is an employee of Pfizer BioTherapeutics, LS is an employee of Amofrix Life Sciences. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Analyzed the data: BP GR BD DR AJ VM GM AP AW. Wrote the paper: BP GR. Designed all experiments and conducted the final data analyses: BP GR. Contributed to the study design: HW. In vitro electrophysiology: BD. Tissue analyses, genotyping and histology: DK SS. Behaviour: DR EP GM AU VM. EEG/activity: AJ AP. PET imaging: AW MM. Amyloid assay: LS.