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Research Article

Loss of the α2β1 Integrin Alters Human Papilloma Virus-Induced Squamous Carcinoma Progression In Vivo and In Vitro

  • Thuy Tran,

    Affiliation: Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Brittney Barlow,

    Affiliation: Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Lynda O'Rear,

    Affiliation: Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Brenda Jarvis,

    Affiliation: Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Zhengzhi Li,

    Affiliation: Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Kent Dickeson,

    Affiliation: Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • William Dupont,

    Affiliation: Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Mary Zutter mail

    mary.zutter@vanderbilt.edu

    Affiliations: Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Published: October 27, 2011
  • DOI: 10.1371/journal.pone.0026858

About the Authors

Thuy Tran, Brittney Barlow, Lynda O'Rear, Brenda Jarvis, Zhengzhi Li, Kent Dickeson, Mary Zutter
Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Mary Zutter
Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
William Dupont
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Corresponding Author

Email: mary.zutter@vanderbilt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TT MZ. Performed the experiments: TT BB LO BJ ZL. Analyzed the data: TT KD WD MZ. Contributed reagents/materials/analysis tools: KD WD MZ. Wrote the paper: TT WD MZ.