About the Authors

Surbhi Jain

Affiliation Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

Ting-Tsung Chang

Contributed equally to this work with: Ting-Tsung Chang, James P. Hamilton

Affiliation Department of Medicine, Infectious Diseases and Signaling Research Center, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Republic of China

James P. Hamilton

Contributed equally to this work with: Ting-Tsung Chang, James P. Hamilton

Affiliation Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Selena Y. Lin

Affiliation Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

Yih-Jyh Lin

Affiliation Department of Surgery, National Cheng Kung University Hospital, Tainan, Taiwan, Republic of China

Alison A. Evans

Affiliation School of Public Health, Drexel University, Philadelphia, Pennsylvania, United States of America

Florin M. Selaru

Affiliation Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Pin- Wen Lin

Affiliation Department of Surgery, National Cheng Kung University Hospital, Tainan, Taiwan, Republic of China

Shun-Hua Chen

Affiliation Department of Microbiology, Medical College, National Cheng Kung University, Tainan, Taiwan, Republic of China

Timothy M. Block

Affiliation Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

Chi-Tan Hu

Affiliation Department of General Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, Republic of China

Wei Song

Affiliation JBS Science Inc., Philadelphia, Pennsylvania, United States of America

Stephen J. Meltzer

Affiliations Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States of America

Ying-Hsiu Su

Ying-hsiu.Su@drexelmed.edu

Affiliation Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

WS, President of the JBS Science Inc. The affiliation of WS with JBS Science Inc. does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. All other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SJ T-TC Y-HS SM WS TB. Performed the experiments: SJ SL. Analyzed the data: AE SJ Y-HS. Contributed reagents/materials/analysis tools: SM T-TC JH Y-JL FS P-WL S-HC C-TH. Wrote the paper: SJ Y-HS SM TB.