About the Authors

Frank H. Lau

Affiliation Center for Regenerative Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Rahul C. Deo

Affiliation Center for Regenerative Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Gregory Mowrer

Affiliation Center for Regenerative Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Joshua Caplin

Affiliation Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Tim Ahfeldt

Affiliations Center for Regenerative Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America

Adam Kaplan

Affiliation Center for Regenerative Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Leon Ptaszek

Affiliation Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Jennifer D. Walker

Affiliation Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Bruce R. Rosengard

Affiliation Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Chad A. Cowan

ccowan@fas.harvard.edu

Affiliations Center for Regenerative Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America

Competing Interests

One research grant from a commercial source (GlaxoSmithKline). This does not alter the authors' adherence to all PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JC LP JDW BRR CAC. Performed the experiments: FHL GM JC TA AK LP JDW BRR CAC. Analyzed the data: FHL RCD GW TA AK CAC. Contributed reagents/materials/analysis tools: FHL RCD JDW BRR CAC. Wrote the paper: FHL RCD GM AK CAC.