About the Authors
- Jon C. Aster
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* E-mail: jaster@rics.bwh.harvard.edu (JCA); wpear@mail.med.upenn.edu (WSP)
Affiliation Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
- Nick Bodnar
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Affiliations Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
- Lanwei Xu
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Affiliation Department of Pathology and Lab Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
- Fredrick Karnell
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Affiliation Department of Pathology and Lab Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
- John M. Milholland
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Affiliation Department of Pathology and Lab Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
- Ivan Maillard
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Affiliation Department of Pathology and Lab Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
- Gavin Histen
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Affiliation Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
- Yunsun Nam
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Affiliation Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
- Stephen C. Blacklow
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Affiliations Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
- Warren S. Pear
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* E-mail: jaster@rics.bwh.harvard.edu (JCA); wpear@mail.med.upenn.edu (WSP)
Affiliation Department of Pathology and Lab Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: JA WSP SCB . Performed the experiments: NB JM FK LX IM GH YN. Analyzed the data: JCA WSP SCB JM FK LX NB IM GH YN. Wrote the paper: JA SCB WSP. Performed structural modeling: YN NB SCB.