Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Identification of Mycobacteria in Routine Clinical Practice

Amel El Khéchine; Carine Couderc; Christophe Flaudrops; Didier Raoult; Michel Drancourt

doi:10.1371/journal.pone.0024720

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Open Access

Peer-reviewed

Research Article

Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Identification of Mycobacteria in Routine Clinical Practice

Amel El Khéchine,

Affiliation URMITE UMR CNRS 6236 IRD198, Institut Hospitalier Universitaire POLMIT, IFR48, Université de la Méditerranée et Pôle de Maladies Infectieuses, Assistance Publique-Hôpitaux de Marseille, Marseille, France
⨯
Carine Couderc,

Affiliation URMITE UMR CNRS 6236 IRD198, Institut Hospitalier Universitaire POLMIT, IFR48, Université de la Méditerranée et Pôle de Maladies Infectieuses, Assistance Publique-Hôpitaux de Marseille, Marseille, France
⨯
Christophe Flaudrops,

Affiliation URMITE UMR CNRS 6236 IRD198, Institut Hospitalier Universitaire POLMIT, IFR48, Université de la Méditerranée et Pôle de Maladies Infectieuses, Assistance Publique-Hôpitaux de Marseille, Marseille, France
⨯
Didier Raoult,

Affiliation URMITE UMR CNRS 6236 IRD198, Institut Hospitalier Universitaire POLMIT, IFR48, Université de la Méditerranée et Pôle de Maladies Infectieuses, Assistance Publique-Hôpitaux de Marseille, Marseille, France
⨯
Michel Drancourt

* E-mail: Michel.Drancourt@univmed.fr

Affiliation URMITE UMR CNRS 6236 IRD198, Institut Hospitalier Universitaire POLMIT, IFR48, Université de la Méditerranée et Pôle de Maladies Infectieuses, Assistance Publique-Hôpitaux de Marseille, Marseille, France
⨯

Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Identification of Mycobacteria in Routine Clinical Practice

Amel El Khéchine,
Carine Couderc,
Christophe Flaudrops,
Didier Raoult,
Michel Drancourt

Published: September 13, 2011
https://doi.org/10.1371/journal.pone.0024720

About the Authors

Amel El Khéchine

Affiliation URMITE UMR CNRS 6236 IRD198, Institut Hospitalier Universitaire POLMIT, IFR48, Université de la Méditerranée et Pôle de Maladies Infectieuses, Assistance Publique-Hôpitaux de Marseille, Marseille, France

Carine Couderc

Christophe Flaudrops

Didier Raoult

Michel Drancourt

* E-mail: Michel.Drancourt@univmed.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DR MD. Performed the experiments: AEK CC CF. Analyzed the data: AEK DR MD. Contributed reagents/materials/analysis tools: DR MD. Wrote the paper: AEK CC CF DR MD.

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Mycobacterium tuberculosis
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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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Mycobacterium avium complex
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Mycobacterium bovis
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Ethanol
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Nontuberculous mycobacteria
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Protein extraction
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Tuberculosis diagnosis and management
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