About the Authors
- Ana Carvalho
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Contributed equally to this work with: Ana Carvalho, Sara K. Olson, Edgar Gutierrez
Affiliation Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America
- Sara K. Olson
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Contributed equally to this work with: Ana Carvalho, Sara K. Olson, Edgar Gutierrez
Affiliation Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America
- Edgar Gutierrez
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Contributed equally to this work with: Ana Carvalho, Sara K. Olson, Edgar Gutierrez
Affiliation Department of Physics, University of California San Diego, La Jolla, California, United States of America
- Kelly Zhang
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Affiliation Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America
- Lisa B. Noble
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Affiliation Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America
- Esther Zanin
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Affiliation Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America
- Arshad Desai
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Affiliation Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America
- Alex Groisman
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* E-mail: koegema@ucsd.edu (KO); agroisman@ucsd.edu (AG)
Affiliation Department of Physics, University of California San Diego, La Jolla, California, United States of America
- Karen Oegema
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* E-mail: koegema@ucsd.edu (KO); agroisman@ucsd.edu (AG)
Affiliation Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: AC SO EG AG KO. Performed the experiments: AC SO EG KZ LN EZ. Analyzed the data: AC SO EG AG KO. Wrote the paper: AC SO AD AG KO. Performed screen to identify permeability genes: SO KZ LN. Optimized perm-1 RNAi: AC SO EZ. Performed drug delivery experiments: AC. Designed microdevice: EG AG. Built microdevices: EG.