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Research Article

Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances

  • Brent L. Williams,

    Affiliation: Center for Infection and Immunity, Columbia University, New York, New York, United States of America

    X
  • Mady Hornig,

    Affiliation: Center for Infection and Immunity, Columbia University, New York, New York, United States of America

    X
  • Timothy Buie,

    Affiliation: Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    X
  • Margaret L. Bauman,

    Affiliation: Department of Neurology, Harvard Medical School and Departments of Neurology and Pediatrics and Learning and Developmental Disabilities Evaluation and Rehabilitation Services (LADDERS), Massachusetts General Hospital, Boston, Massachusetts, United States of America

    X
  • Myunghee Cho Paik,

    Affiliation: Department of Biostatistics, Columbia University, Mailman School of Public Health, New York, New York, United States of America

    X
  • Ivan Wick,

    Affiliation: Center for Infection and Immunity, Columbia University, New York, New York, United States of America

    X
  • Ashlee Bennett,

    Affiliation: Center for Infection and Immunity, Columbia University, New York, New York, United States of America

    X
  • Omar Jabado,

    Affiliation: Center for Infection and Immunity, Columbia University, New York, New York, United States of America

    X
  • David L. Hirschberg,

    Affiliation: Center for Infection and Immunity, Columbia University, New York, New York, United States of America

    X
  • W. Ian Lipkin mail

    wil2001@columbia.edu

    Affiliation: Center for Infection and Immunity, Columbia University, New York, New York, United States of America

    X
  • Published: September 16, 2011
  • DOI: 10.1371/journal.pone.0024585

About the Authors

Brent L. Williams, Mady Hornig, Ivan Wick, Ashlee Bennett, Omar Jabado, David L. Hirschberg, W. Ian Lipkin
Center for Infection and Immunity, Columbia University, New York, New York, United States of America
Timothy Buie
Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital, Boston, Massachusetts, United States of America
Margaret L. Bauman
Department of Neurology, Harvard Medical School and Departments of Neurology and Pediatrics and Learning and Developmental Disabilities Evaluation and Rehabilitation Services (LADDERS), Massachusetts General Hospital, Boston, Massachusetts, United States of America
Myunghee Cho Paik
Department of Biostatistics, Columbia University, Mailman School of Public Health, New York, New York, United States of America

Corresponding Author

Email: wil2001@columbia.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BLW MH TB MLB WIL. Performed the experiments: BLW DLH AB. Analyzed the data: BLW MH MCP IW OJ. Wrote the paper: BLW MH WIL. Created Figures and Tables: BLW. Supervised research: WIL.