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Research Article

A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses

  • Juan García-Arriaza,

    Affiliation: Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

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  • José Luis Nájera,

    Affiliation: Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

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  • Carmen E. Gómez,

    Affiliation: Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

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  • Nolawit Tewabe,

    Affiliation: Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

    Current address: Takeda Pharmaceutical Company, London, United Kingdom

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  • Carlos Oscar S. Sorzano,

    Affiliation: Biocomputing Unit, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

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  • Thierry Calandra,

    Affiliation: Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

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  • Thierry Roger,

    Affiliation: Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

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  • Mariano Esteban mail

    mesteban@cnb.csic.es

    Affiliation: Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain

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  • Published: August 31, 2011
  • DOI: 10.1371/journal.pone.0024244

About the Authors

Juan García-Arriaza, José Luis Nájera, Carmen E. Gómez, Nolawit Tewabe, Mariano Esteban
Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
Carlos Oscar S. Sorzano
Biocomputing Unit, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
Thierry Calandra, Thierry Roger
Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

Corresponding Author

Email: mesteban@cnb.csic.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JG-A ME. Performed the experiments: JG-A JLN NT. Analyzed the data: JG-A COSS. Contributed reagents/materials/analysis tools: JG-A CEG TC TR ME. Wrote the paper: JG-A ME.