SLOB, a SLOWPOKE Channel Binding Protein, Regulates Insulin Pathway Signaling and Metabolism in Drosophila

Amanda L. Sheldon; Jiaming Zhang; Hong Fei; Irwin B. Levitan

doi:10.1371/journal.pone.0023343

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Open Access

Peer-reviewed

Research Article

SLOB, a SLOWPOKE Channel Binding Protein, Regulates Insulin Pathway Signaling and Metabolism in Drosophila

Amanda L. Sheldon,

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Jiaming Zhang,

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Hong Fei,

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Irwin B. Levitan

* E-mail: Irwin.Levitan@Jefferson.edu

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯

SLOB, a SLOWPOKE Channel Binding Protein, Regulates Insulin Pathway Signaling and Metabolism in Drosophila

Amanda L. Sheldon,
Jiaming Zhang,
Hong Fei,
Irwin B. Levitan

Published: August 5, 2011
https://doi.org/10.1371/journal.pone.0023343

About the Authors

Amanda L. Sheldon

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Jiaming Zhang

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Hong Fei

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Irwin B. Levitan

* E-mail: Irwin.Levitan@Jefferson.edu

Affiliation Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ALS IBL. Performed the experiments: ALS JZ. Analyzed the data: ALS. Contributed reagents/materials/analysis tools: HF. Wrote the paper: ALS IBL.

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Trehalose
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Glucose
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Gene expression
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Insulin
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Drosophila melanogaster
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Glucose metabolism
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Protein metabolism
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Insulin signaling
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