About the Authors

Yoshiyuki Watanabe

Contributed equally to this work with: Yoshiyuki Watanabe, Ryan J. Castoro

ponponta@marianna-u.ac.jp

Affiliations Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America, Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan

Ryan J. Castoro

Contributed equally to this work with: Yoshiyuki Watanabe, Ryan J. Castoro

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Hyun Soo Kim

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Brittany North

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Ritsuko Oikawa

Affiliation Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan

Tetsuya Hiraishi

Affiliation Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan

Saira S. Ahmed

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Woonbok Chung

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Mee-Yon Cho

Affiliation Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea

Minoru Toyota

Affiliation Department of Biochemistry, Sapporo Medical University, Sapporo, Hokkaido, Japan

Fumio Itoh

Affiliation Division of Gastroenterology and Hepatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan

Marcos R. H. Estecio

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Lanlan Shen

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Jaroslav Jelinek

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Jean-Pierre J. Issa

Affiliation Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YW J-PJI. Performed the experiments: YW RJC RO SSA MT. Analyzed the data: YW RJC. Contributed reagents/materials/analysis tools: HSK WC M-YC FI MRHE LS JJ J-PJI TH. Wrote the paper: YW BN RJC J-PJI.