About the Authors

Juliana Benito

Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Yuexi Shi

Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Barbara Szymanska

Affiliation C25 Lowy Cancer Research Centre, Children's Cancer Institute Australia for Medical Research, University of New South Wales, Randwick, New South Wales, Australia

Hernan Carol

Affiliation C25 Lowy Cancer Research Centre, Children's Cancer Institute Australia for Medical Research, University of New South Wales, Randwick, New South Wales, Australia

Ingrid Boehm

Affiliation C25 Lowy Cancer Research Centre, Children's Cancer Institute Australia for Medical Research, University of New South Wales, Randwick, New South Wales, Australia

Hongbo Lu

Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Sergej Konoplev

Affiliation Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Wendy Fang

Affiliation Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Patrick A. Zweidler-McKay

Affiliation Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Dario Campana

Affiliation St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Gautam Borthakur

Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Carlos Bueso-Ramos

Affiliation Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Elizabeth Shpall

Affiliation Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Deborah A. Thomas

Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Craig T. Jordan

Affiliation School of Medicine and Dentistry, University of Rochester, Rochester, New York, United States of America

Hagop Kantarjian

Affiliation Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

William R. Wilson

Affiliation Auckland Cancer Society Research Center, The University of Auckland, Auckland, New Zealand

Richard Lock

Affiliation Auckland Cancer Society Research Center, The University of Auckland, Auckland, New Zealand

Michael Andreeff

Affiliations Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Marina Konopleva

mkonople@mdanderson.org

Affiliations Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: Dr. William R. Wilson holds stock in PROACTA Inc. and is a consultant to the company. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JB BS HC IB SK PAZ-M DC GB CB-R ES DAT CTJ HK WRW RL MA MK. Performed the experiments: JB YS BS HC IB HL SK WF. Analyzed the data: JB YS BS HC IB HL SK PAZ-M WRW RL MA MK. Contributed reagents/materials/analysis tools: DC CTJ. Wrote the paper: JB RL MK. Revised manuscript for intellectual content: YS HL SK PAZ-M DC CB-R ES DAT CTJ HK WRW RL MA MK.