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Research Article

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

  • Ankit Gupta equal contributor,

    equal contributor Contributed equally to this work with: Ankit Gupta, Pruthvi Nagilla

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Pruthvi Nagilla equal contributor,

    equal contributor Contributed equally to this work with: Ankit Gupta, Pruthvi Nagilla

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Hai-Son Le,

    Affiliation: Department of Machine Learning, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

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  • Coulton Bunney,

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Courtney Zych,

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Anbupalam Thalamuthu,

    Affiliation: Human Genetics, Genome Institute of Singapore, Singapore

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  • Ziv Bar-Joseph,

    Affiliation: Department of Machine Learning, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

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  • Sinnakaruppan Mathavan,

    Affiliation: Human Genetics, Genome Institute of Singapore, Singapore

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  • Velpandi Ayyavoo mail

    velpandi@pitt.edu

    Affiliation: Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Published: July 28, 2011
  • DOI: 10.1371/journal.pone.0022730

About the Authors

Ankit Gupta, Pruthvi Nagilla, Coulton Bunney, Courtney Zych, Velpandi Ayyavoo
Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
Hai-Son Le, Ziv Bar-Joseph
Department of Machine Learning, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
Anbupalam Thalamuthu, Sinnakaruppan Mathavan
Human Genetics, Genome Institute of Singapore, Singapore

Corresponding Author

Email: velpandi@pitt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AG VA. Performed the experiments: AG PN CB CZ. Analyzed the data: AG PN H-SL CB AT ZB-J SM VA. Wrote the paper: AG CZ ZB-J VA.