About the Authors

Daniel J. Anderson

anderson.daniel@gene.com

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America

Jenni K. Durieux

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America

Kyung Song

Affiliation Department of Cancer Signaling, Genentech, Inc., South San Francisco, California, United States of America

Ryan Alvarado

Affiliation Department of Cancer Signaling, Genentech, Inc., South San Francisco, California, United States of America

Peter K. Jackson

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America

Georgia Hatzivassiliou

Affiliation Department of Cancer Signaling, Genentech, Inc., South San Francisco, California, United States of America

Mary J. C. Ludlam

Affiliation Department of Cell Regulation, Genentech, Inc., South San Francisco, California, United States of America

Competing Interests

All authors are paid employees of Genentech, Inc., which is the funder of the reported studies. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DJA GH MJCL. Performed the experiments: DJA JKD KS RA. Analyzed the data: DJA KS RA GH. Wrote the paper: DJA JKD PKJ GH MJCL.