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Research Article

Tenascin-C Enhances Pancreatic Cancer Cell Growth and Motility and Affects Cell Adhesion through Activation of the Integrin Pathway

  • Igor Paron equal contributor,

    equal contributor Contributed equally to this work with: Igor Paron, Sonja Berchtold

    Affiliations: Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Pathology, Technische Universität München, Munich, Germany

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  • Sonja Berchtold equal contributor,

    equal contributor Contributed equally to this work with: Igor Paron, Sonja Berchtold

    Affiliations: Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Pathology, Technische Universität München, Munich, Germany

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  • Julia Vörös,

    Affiliation: Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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  • Madhavi Shamarla,

    Affiliation: Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

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  • Mert Erkan,

    Affiliation: Department of General Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

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  • Heinz Höfler,

    Affiliations: Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Pathology, Technische Universität München, Munich, Germany

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  • Irene Esposito mail

    esposito@lrz.tum.de

    Affiliations: Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, Institute of Pathology, Technische Universität München, Munich, Germany

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  • Published: June 29, 2011
  • DOI: 10.1371/journal.pone.0021684

About the Authors

Igor Paron, Sonja Berchtold, Julia Vörös, Madhavi Shamarla, Heinz Höfler, Irene Esposito
Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
Igor Paron, Sonja Berchtold, Heinz Höfler, Irene Esposito
Institute of Pathology, Technische Universität München, Munich, Germany
Mert Erkan
Department of General Surgery, Klinikum rechts der Isar, Technische Universität München, Munich, Germany

Corresponding Author

Email: esposito@lrz.tum.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IP SB HH IE. Performed the experiments: IP SB JV MS ME. Analyzed the data: IP SB JV MS IE. Contributed reagents/materials/analysis tools: ME HH IE. Wrote the paper: IP SB IE.