About the Authors

Sydney X. Lu

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Lucy W. Kappel

Contributed equally to this work with: Lucy W. Kappel, Anne-Marie Charbonneau-Allard, Renée Atallah

Affiliations Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Department of Immunology, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America

Anne-Marie Charbonneau-Allard

Contributed equally to this work with: Lucy W. Kappel, Anne-Marie Charbonneau-Allard, Renée Atallah

Affiliation Goodman Cancer Center and Departments of Biochemistry, Medicine, and Oncology, McGill Cancer Center, Montreal, Quebec, Canada

Renée Atallah

Contributed equally to this work with: Lucy W. Kappel, Anne-Marie Charbonneau-Allard, Renée Atallah

Affiliation Goodman Cancer Center and Departments of Biochemistry, Medicine, and Oncology, McGill Cancer Center, Montreal, Quebec, Canada

Amanda M. Holland

Affiliations Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Department of Immunology, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America

Claire Turbide

Affiliation Goodman Cancer Center and Departments of Biochemistry, Medicine, and Oncology, McGill Cancer Center, Montreal, Quebec, Canada

Vanessa M. Hubbard

Affiliations Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Jimmy A. Rotolo

Affiliation Department of Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Marsinay Smith

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

David Suh

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Christopher King

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Uttam K. Rao

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Nury Yim

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Johanne L. Bautista

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Robert R. Jenq

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Olaf Penack

Affiliations Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Department of Hematology and Oncology, Charité CBF - Universitätsmedizin Berlin, Berlin, Germany

Il-Kang Na

Affiliations Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Department of Hematology and Oncology, Charité CBF - Universitätsmedizin Berlin, Berlin, Germany

Chen Liu

Affiliation Department of Pathology, University of Florida College of Medicine, Gainesville, Florida, United States of America

George Murphy

Affiliation Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Onder Alpdogan

Affiliations Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Department of Medicine, Yale University Medical School, New Haven, Connecticut, United States of America

Richard S. Blumberg

Affiliation Department of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

Fernando Macian

Affiliation Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, United States of America

Kathryn V. Holmes

Affiliation Department of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America

Nicole Beauchemin

These authors also contributed equally to this work.

Affiliation Goodman Cancer Center and Departments of Biochemistry, Medicine, and Oncology, McGill Cancer Center, Montreal, Quebec, Canada

Marcel R. M. van den Brink

These authors also contributed equally to this work.

Affiliation Department of Immunology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SXL LWK A-MC-A RA AMH CT VMH JAR CL GM OA MRMvdB. Performed the experiments: SXL LWK A-MC-A RA AMH CT VMH JAR CL GM MS DS CK UKR NY JLB RRJ OP I-KN. Analyzed the data: SXL JAR CL GM OA MRMvdB. Contributed reagents/materials/analysis tools: RSB FM KVH NB. Wrote the paper: SXL OA MRMvdB.