About the Authors

Hedi Schelleman

hschelle@mail.med.upenn.edu

Affiliation Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Colleen M. Brensinger

Affiliation Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Warren B. Bilker

Affiliations Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Sean Hennessy

Affiliations Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

Dr. Schelleman has had travel to scientific conferences paid for by pharmacoepidemiology training funds contributed by pharmaceutical manufacturers (Abbott, Amgen, Berlex, Merck, Novartis, Pfizer, Roche, Sanofi-aventis en Wyeth). Ms. Brensinger has consulted for a law firm (Kaye Scholer LLP) representing Pfizer, unrelated to warfarin and antidepressants. Dr. Bilker has consulted for Johnson & Johnson and Astra Zeneca, unrelated to warfarin and antidepressants. Dr. Hennessy has received research funding from Shire and Tekeda, and consulted for Bayer, Teva, Wyeth, Astra-Zeneca, Endo and Amgen, all unrelated to warfarin and antidepressants. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HS CMB WBB SH. Performed the experiments: HS CMB WBB SH. Analyzed the data: HS CMB WBB SH. Wrote the paper: HS CMB WBB SH.