DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange

Hungjiun Liaw; Deokjae Lee; Kyungjae Myung

doi:10.1371/journal.pone.0021424

Loading metrics

Open Access

Peer-reviewed

Research Article

DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange

Hungjiun Liaw,

Current address: Department of Life Sciences, National Cheng Kung University, Tainan City, Taiwan

Affiliation Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Deokjae Lee,

Affiliation Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Kyungjae Myung

* E-mail: kmyung@mail.nih.gov

Affiliation Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange

Hungjiun Liaw,
Deokjae Lee,
Kyungjae Myung

Published: June 22, 2011
https://doi.org/10.1371/journal.pone.0021424

About the Authors

Hungjiun Liaw

Current address: Department of Life Sciences, National Cheng Kung University, Tainan City, Taiwan

Affiliation Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Deokjae Lee

Affiliation Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Kyungjae Myung

* E-mail: kmyung@mail.nih.gov

Affiliation Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HL DL KM. Performed the experiments: HL DL. Analyzed the data: HL DL KM. Contributed reagents/materials/analysis tools: HL KM. Wrote the paper: HL KM.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
DNA damage
Is the Subject Area "DNA damage" applicable to this article?

Thanks for your feedback.
DNA replication
Is the Subject Area "DNA replication" applicable to this article?

Thanks for your feedback.
Mitosis
Is the Subject Area "Mitosis" applicable to this article?

Thanks for your feedback.
DNA repair
Is the Subject Area "DNA repair" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
Recombinase polymerase amplification
Is the Subject Area "Recombinase polymerase amplification" applicable to this article?

Thanks for your feedback.