About the Authors

Mirjam J. Knol

m.j.knol@umcutrecht.nl

Affiliation Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands

Ruben G. Duijnhoven

Affiliation Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands

Diederick E. Grobbee

Affiliation Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands

Karel G. M. Moons

Affiliation Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands

Rolf H. H. Groenwold

Affiliation Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands

Competing Interests

The authors have read the journal's policy and have the following conflicts: funding for this project was received by the Dutch Top Institute Pharma, a public-private partnership. The funders did not have any influence on the content of the manuscript. The manuscript does not report on products of the funders. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MJK RHHG. Performed the experiments: MJK RGD RHHG. Analyzed the data: MJK RHHG. Wrote the paper: MJK RHHG RGD. Critically reviewed the manuscript: DEG KGMM RHHG.