Cadmium Induces Transcription Independently of Intracellular Calcium Mobilization

Brooke E. Tvermoes; Gary S. Bird; Jonathan H. Freedman

doi:10.1371/journal.pone.0020542

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Open Access

Peer-reviewed

Research Article

Cadmium Induces Transcription Independently of Intracellular Calcium Mobilization

Brooke E. Tvermoes,

Affiliations Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), Research Triangle Park, North Carolina, United States of America, Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
⨯
Gary S. Bird,

Affiliation Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), Research Triangle Park, North Carolina, United States of America
⨯
Jonathan H. Freedman

* E-mail: freedma1@niehs.nih.gov

Affiliation Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), Research Triangle Park, North Carolina, United States of America
⨯

Cadmium Induces Transcription Independently of Intracellular Calcium Mobilization

Brooke E. Tvermoes,
Gary S. Bird,
Jonathan H. Freedman

Published: June 9, 2011
https://doi.org/10.1371/journal.pone.0020542

About the Authors

Brooke E. Tvermoes

Affiliations Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), Research Triangle Park, North Carolina, United States of America, Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America

Gary S. Bird

Affiliation Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), Research Triangle Park, North Carolina, United States of America

Jonathan H. Freedman

* E-mail: freedma1@niehs.nih.gov

Affiliation Laboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), Research Triangle Park, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BET GSB JHF. Performed the experiments: BET GSB. Analyzed the data: BET GSB. Contributed reagents/materials/analysis tools: BET GSB. Wrote the paper: BET GSB JHF.

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Cadmium
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Calcium signaling
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DNA transcription
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Gene expression
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Bone and mineral metabolism
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Messenger RNA
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Transcription factors
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Transcriptional control
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