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Research Article

Sero-Prevalence and Incidence of A/H1N1 2009 Influenza Infection in Scotland in Winter 2009–2010

  • Nigel J. McLeish,

    Affiliation: Centre for Infectious Diseases, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Peter Simmonds,

    Affiliation: Centre for Infectious Diseases, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Chris Robertson,

    Affiliations: Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom, Health Protection Scotland, Glasgow, United Kingdom

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  • Ian Handel,

    Affiliation: Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom

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  • Mark McGilchrist,

    Affiliation: Health Informatics Centre, University of Dundee, Dundee, United Kingdom

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  • Brajendra K. Singh,

    Affiliation: Centre for Infectious Diseases, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Shona Kerr,

    Affiliation: Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

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  • Margo E. Chase-Topping,

    Affiliation: Centres for Immunity, Infection and Evolution, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Katy Sinka,

    Affiliation: Health Protection Scotland, Glasgow, United Kingdom

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  • Mark Bronsvoort,

    Affiliation: Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom

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  • David J. Porteous,

    Affiliation: Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

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  • William Carman,

    Affiliation: West of Scotland Specialist Virology Centre, Gartnavel General Hospital, Glasgow, United Kingdom

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  • James McMenamin,

    Affiliation: Health Protection Scotland, Glasgow, United Kingdom

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  • Andrew Leigh-Brown,

    Affiliation: Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Mark E. J. Woolhouse mail

    mark.woolhouse@ed.ac.uk

    Affiliation: Centre for Infectious Diseases, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Published: June 08, 2011
  • DOI: 10.1371/journal.pone.0020358

About the Authors

Nigel J. McLeish, Peter Simmonds, Brajendra K. Singh, Mark E. J. Woolhouse
Centre for Infectious Diseases, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom
Chris Robertson
Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom
Chris Robertson, Katy Sinka, James McMenamin
Health Protection Scotland, Glasgow, United Kingdom
Ian Handel, Mark Bronsvoort
Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom
Mark McGilchrist
Health Informatics Centre, University of Dundee, Dundee, United Kingdom
Shona Kerr, David J. Porteous
Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom
Margo E. Chase-Topping
Centres for Immunity, Infection and Evolution, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom
William Carman
West of Scotland Specialist Virology Centre, Gartnavel General Hospital, Glasgow, United Kingdom
Andrew Leigh-Brown
Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

Corresponding Author

Email: mark.woolhouse@ed.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PS JM AL-B MEJW. Performed the experiments: NJM. Analyzed the data: CR IH BKS MEC-T MB. Contributed reagents/materials/analysis tools: PS WC. Wrote the paper: NJM MEJW. Arranged access to samples: MM SK DJP. Compiled vaccination data: KS.