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Research Article

Incidence of Sarcoma Histotypes and Molecular Subtypes in a Prospective Epidemiological Study with Central Pathology Review and Molecular Testing

  • Françoise Ducimetière mail,

    ducimeti@lyon.fnclcc.fr

    Affiliation: Université de Lyon, Cancer Centre Leon Berard, EA 4129, Lyon, France

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  • Antoine Lurkin,

    Affiliation: Université de Lyon, Cancer Centre Leon Berard, EA 4129, Lyon, France

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  • Dominique Ranchère-Vince,

    Affiliation: Université de Lyon, Cancer Centre Leon Berard, Department of Pathology, Lyon, France

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  • Anne-Valérie Decouvelaere,

    Affiliation: Université de Lyon, Cancer Centre Leon Berard, Department of Pathology, Lyon, France

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  • Michel Péoc'h,

    Affiliation: Université de Saint-Etienne, Centre Hospitalier Universitaire, Department of Pathology, Saint-Etienne, France

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  • Luc Istier,

    Affiliation: Laboratory of Pathology, Pringy, France

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  • Philippe Chalabreysse,

    Affiliation: Laboratory of Pathology, Cypath, Lyon, France

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  • Christine Muller,

    Affiliation: Laboratory of Pathology, Grenoble, France

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  • Laurent Alberti,

    Affiliation: Université de Lyon, Cancer Centre Leon Berard, INSERM U590, Lyon, France

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  • Pierre-Paul Bringuier,

    Affiliation: Université de Lyon, Hospices Civils de Lyon, Hôpital Edouard Herriot, Department of Pathology, Lyon, France

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  • Jean-Yves Scoazec,

    Affiliation: Université de Lyon, Hospices Civils de Lyon, Hôpital Edouard Herriot, Department of Pathology, Lyon, France

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  • Anne-Marie Schott,

    Affiliation: Université de Lyon, Hospices Civils de Lyon, Pôle IMER, Lyon, France

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  • Christophe Bergeron,

    Affiliation: Institut d'Hématologie et d'Oncologie Pédiatrique, Department of Paediatrics, Lyon, France

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  • Dominic Cellier,

    Affiliation: Merck Serono, Scientific Relation, Lyon, France

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  • Jean-Yves Blay,

    Affiliation: Université de Lyon, Cancer Centre Leon Berard, INSERM U590, Lyon, France

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  • Isabelle Ray-Coquard

    Affiliation: Université de Lyon, Cancer Centre Leon Berard, EA 4129, Lyon, France

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  • Published: August 03, 2011
  • DOI: 10.1371/journal.pone.0020294

About the Authors

Françoise Ducimetière, Antoine Lurkin, Isabelle Ray-Coquard
Université de Lyon, Cancer Centre Leon Berard, EA 4129, Lyon, France
Dominique Ranchère-Vince, Anne-Valérie Decouvelaere
Université de Lyon, Cancer Centre Leon Berard, Department of Pathology, Lyon, France
Michel Péoc'h
Université de Saint-Etienne, Centre Hospitalier Universitaire, Department of Pathology, Saint-Etienne, France
Luc Istier
Laboratory of Pathology, Pringy, France
Philippe Chalabreysse
Laboratory of Pathology, Cypath, Lyon, France
Christine Muller
Laboratory of Pathology, Grenoble, France
Laurent Alberti, Jean-Yves Blay
Université de Lyon, Cancer Centre Leon Berard, INSERM U590, Lyon, France
Pierre-Paul Bringuier, Jean-Yves Scoazec
Université de Lyon, Hospices Civils de Lyon, Hôpital Edouard Herriot, Department of Pathology, Lyon, France
Anne-Marie Schott
Université de Lyon, Hospices Civils de Lyon, Pôle IMER, Lyon, France
Christophe Bergeron
Institut d'Hématologie et d'Oncologie Pédiatrique, Department of Paediatrics, Lyon, France
Dominic Cellier
Merck Serono, Scientific Relation, Lyon, France

Corresponding Author

Email: ducimeti@lyon.fnclcc.fr

Competing Interests

The authors would like to specify that Dr. Dominic Cellier is the scientific relationship director of Merck-Serono. Merck-Serono provides financial support. The authors confirm that this does not alter their adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DR-V DC J-YB IRC. Performed the experiments: FD AL DR-V A-VD MP LI PC CM LA P-PB J-YS. Analyzed the data: FD AL DR-V A-VD A-MS CB J-YB IR-C. Contributed reagents/materials/analysis tools: DR-V A-VD MP LI PC CM LA P-PB J-YS. Wrote the paper: FD AL DR-V A-VD J-YB IR-C.