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Research Article

The Sensitivity of Massively Parallel Sequencing for Detecting Candidate Infectious Agents Associated with Human Tissue

  • Richard A. Moore equal contributor mail,

    equal contributor Contributed equally to this work with: Richard A. Moore, René L. Warren

    rmoore@bcgsc.ca

    Affiliation: Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • René L. Warren equal contributor,

    equal contributor Contributed equally to this work with: Richard A. Moore, René L. Warren

    Affiliation: Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

    X
  • J. Douglas Freeman,

    Affiliation: Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Julia A. Gustavsen,

    Affiliation: Department of Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia, Canada

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  • Caroline Chénard,

    Affiliation: Department of Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia, Canada

    X
  • Jan M. Friedman,

    Affiliation: Department of Medical Genetics, University of British Columbia, Child and Family Research Institute, Vancouver, British Columbia, Canada

    X
  • Curtis A. Suttle,

    Affiliation: Departments of Earth and Ocean Sciences, Botany, and Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

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  • Yongjun Zhao,

    Affiliation: Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Robert A. Holt

    Affiliation: Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada

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  • Published: May 13, 2011
  • DOI: 10.1371/journal.pone.0019838

About the Authors

Richard A. Moore, René L. Warren, J. Douglas Freeman, Yongjun Zhao, Robert A. Holt
Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada
Julia A. Gustavsen, Caroline Chénard
Department of Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia, Canada
Jan M. Friedman
Department of Medical Genetics, University of British Columbia, Child and Family Research Institute, Vancouver, British Columbia, Canada
Curtis A. Suttle
Departments of Earth and Ocean Sciences, Botany, and Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

Corresponding Author

Email: rmoore@bcgsc.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RAM RAH JMF CAS. Performed the experiments: RAM JAG CC JDF YZ. Analyzed the data: RLW RAM. Contributed reagents/materials/analysis tools: RLW CAS. Wrote the paper: RAM RAH RLW.