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Research Article

The Interplay between NF-kappaB and E2F1 Coordinately Regulates Inflammation and Metabolism in Human Cardiac Cells

  • Xavier Palomer equal contributor,

    equal contributor Contributed equally to this work with: Xavier Palomer, David Álvarez-Guardia

    Affiliation: Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona) and CIBERDEM, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain

    X
  • David Álvarez-Guardia equal contributor,

    equal contributor Contributed equally to this work with: Xavier Palomer, David Álvarez-Guardia

    Affiliation: Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona) and CIBERDEM, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain

    X
  • Mercy M. Davidson,

    Affiliation: Department of Radiation Oncology, Columbia University, New York, New York, United States of America

    X
  • Tung O. Chan,

    Affiliation: Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Arthur M. Feldman,

    Affiliation: Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

    X
  • Manuel Vázquez-Carrera mail

    mvazquezcarrera@ub.edu

    Affiliation: Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona) and CIBERDEM, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain

    X
  • Published: May 23, 2011
  • DOI: 10.1371/journal.pone.0019724

About the Authors

Xavier Palomer, David Álvarez-Guardia, Manuel Vázquez-Carrera
Department of Pharmacology and Therapeutic Chemistry, IBUB (Institut de Biomedicina de la Universitat de Barcelona) and CIBERDEM, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain
Mercy M. Davidson
Department of Radiation Oncology, Columbia University, New York, New York, United States of America
Tung O. Chan, Arthur M. Feldman
Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: mvazquezcarrera@ub.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MVC XP. Performed the experiments: XP DAG. Analyzed the data: MVC XP DAG. Contributed reagents/materials/analysis tools: MMD TOC AMF. Wrote the paper: MVC XP.