About the Authors

Delphine M. Saulnier

Delphine.Saulnier@nizo.nl

Affiliations Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pathology, Texas Children's Hospital, Houston, Texas, United States of America

Filipe Santos

Affiliations Center for Integrative Bioinformatics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Netherlands Consortium for Systems Biology, Delft, The Netherlands

Stefan Roos

Affiliation Department of Microbiology, Swedish University of Agricultural Sciences, Uppsala, Sweden

Toni-Ann Mistretta

Affiliation Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America

Jennifer K. Spinler

Affiliations Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pathology, Texas Children's Hospital, Houston, Texas, United States of America

Douwe Molenaar

Affiliations Center for Integrative Bioinformatics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Netherlands Consortium for Systems Biology, Delft, The Netherlands

Bas Teusink

Affiliations Center for Integrative Bioinformatics, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Netherlands Consortium for Systems Biology, Delft, The Netherlands

James Versalovic

Affiliations Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America, Department of Translational Biology and Molecular Medicine Program, Baylor College of Medicine, Houston, Texas, United States of America, Department of Pathology, Texas Children's Hospital, Houston, Texas, United States of America

Competing Interests

JV receives financial research support (no salary) and holds a patent with Biogaia since 2004, Anti-Inflammatory Activity from Lactic Acid Bacteria (WO/2004/069178). JV and DMS have a patent pending with Biogaia but not related to the work and research presented in this manuscript. JV serves as a scientific advisor for Danone. However, this does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in PLoS ONE's guide for authors. All bacterial genome sequences presented in this manuscript are publicly available on National Center for Biotechnology Information (NCBI). All microarray data have also been deposited into a public database (GEO). All bacterial strains are deposited in public strain collections (ATCC, BEI), and available to everyone.

Author Contributions

Conceived and designed the experiments: DMS FS JV. Performed the experiments: DMS FS DM. Analyzed the data: DMS FS DM TM. Contributed reagents/materials/analysis tools: FS BT JV. Wrote the paper: DMS FS SR JS JV. Served as Principal Investigator of the study: JV. Provided financial support: JV. Supervised the experimental studies: JV.