About the Authors

Jee-Hyun Um

Affiliation Laboratory of Obesity and Aging Research, Genetics and Developmental Biology Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Julie S. Pendergast

Affiliation Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, United States of America

Danielle A. Springer

Affiliation Mouse Phenotyping Core Facility, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Marc Foretz

Affiliations Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, INSERM, U567, Paris, France

Benoit Viollet

Affiliations Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France, INSERM, U567, Paris, France

Alexandra Brown

Affiliation Laboratory of Obesity and Aging Research, Genetics and Developmental Biology Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Myung K. Kim

Affiliation Laboratory of Obesity and Aging Research, Genetics and Developmental Biology Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Shin Yamazaki

Affiliation Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, United States of America

Jay H. Chung

chungj@nhlbi.nih.gov

Affiliation Laboratory of Obesity and Aging Research, Genetics and Developmental Biology Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

Author Shin Yamazaki is an Academic Editor of PLoS ONE.

Author Contributions

Conceived and designed the experiments: JHU JHC SY. Performed the experiments: JHU JSP DAS SY. Analyzed the data: JHU JSP SY MKK DAS JHC. Contributed reagents/materials/analysis tools: MF BV. Wrote the paper: JHU JHC JSP SY AB.