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Research Article

Geographic Differences in Time to Culture Conversion in Liquid Media: Tuberculosis Trials Consortium Study 28. Culture Conversion Is Delayed in Africa

  • William R. Mac Kenzie mail,

    wrm0@cdc.gov

    Affiliation: Tuberculosis Trials Consortium, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America

    X
  • Charles M. Heilig,

    Affiliation: Tuberculosis Trials Consortium, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America

    X
  • Lorna Bozeman,

    Affiliation: Tuberculosis Trials Consortium, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America

    X
  • John L. Johnson,

    Affiliation: Tuberculosis Research Unit, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America

    X
  • Grace Muzanye,

    Affiliation: Uganda-Case Western Reserve University Research Collaboration, Makerere University, Mulago Hospital, Kampala, Uganda, United States of America

    X
  • Denise Dunbar,

    Affiliation: Mycobacteriology Mycology Laboratory, Texas Department of State Health Services, Austin, Texas, United States of America

    X
  • Kenneth C. Jost Jr,

    Affiliation: Mycobacteriology Mycology Laboratory, Texas Department of State Health Services, Austin, Texas, United States of America

    X
  • Lois Diem,

    Affiliation: Laboratory Branch, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America

    X
  • Beverly Metchock,

    Affiliation: Laboratory Branch, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America

    X
  • Kathleen Eisenach,

    Affiliation: University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America

    X
  • Susan Dorman,

    Affiliation: Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Stefan Goldberg

    Affiliation: Tuberculosis Trials Consortium, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America

    X
  • Published: April 11, 2011
  • DOI: 10.1371/journal.pone.0018358

About the Authors

William R. Mac Kenzie, Charles M. Heilig, Lorna Bozeman, Stefan Goldberg
Tuberculosis Trials Consortium, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America
John L. Johnson
Tuberculosis Research Unit, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
Grace Muzanye
Uganda-Case Western Reserve University Research Collaboration, Makerere University, Mulago Hospital, Kampala, Uganda, United States of America
Denise Dunbar, Kenneth C. Jost Jr
Mycobacteriology Mycology Laboratory, Texas Department of State Health Services, Austin, Texas, United States of America
Lois Diem, Beverly Metchock
Laboratory Branch, Division of Tuberculosis Elimination, Centers for Disease Control, Atlanta, Georgia, United States of America
Kathleen Eisenach
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
Susan Dorman
Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Corresponding Author

Email: wrm0@cdc.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Data Interpretation: WRM LB JLJ DD KCJ BM KE SD SG. Critical Revision of Manuscript: SD LB JLJ SG GM DD KCJ LD BM KE. Conceived and designed the experiments: ARM CMH SG. Performed the experiments: LB JLJ GM DD KCJ LD BM KE. Analyzed the data: CMH. Wrote the paper: WRM CMH.