# wombat urls ß PLOS ONE: Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings
Advertisement
Research Article

Leukocyte Telomere Length in Major Depression: Correlations with Chronicity, Inflammation and Oxidative Stress - Preliminary Findings

  • Owen M. Wolkowitz mail,

    owen.wolkowitz@ucsf.edu

    Affiliation: Department of Psychiatry, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Synthia H. Mellon,

    Affiliation: Department of OB-GYN and Reproductive Sciences, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Elissa S. Epel,

    Affiliation: Department of Psychiatry and Health Psychology Program, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Jue Lin,

    Affiliation: Department of Biochemistry and Biophysics, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Firdaus S. Dhabhar,

    Affiliation: Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Yali Su,

    Affiliation: Kronos Science Laboratory, Phoenix, Arizona, United States of America

    X
  • Victor I. Reus,

    Affiliation: Department of Psychiatry, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Rebecca Rosser,

    Affiliation: Department of Psychiatry, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Heather M. Burke,

    Affiliation: Department of Psychiatry and Health Psychology Program, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Eve Kupferman,

    Affiliation: Department of Psychiatry, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Mariana Compagnone,

    Affiliation: Department of Psychiatry, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • J. Craig Nelson,

    Affiliation: Department of Psychiatry, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Elizabeth H. Blackburn

    Affiliation: Department of Biochemistry and Biophysics, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America

    X
  • Published: March 23, 2011
  • DOI: 10.1371/journal.pone.0017837

About the Authors

Owen M. Wolkowitz, Victor I. Reus, Rebecca Rosser, Eve Kupferman, Mariana Compagnone, J. Craig Nelson
Department of Psychiatry, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America
Synthia H. Mellon
Department of OB-GYN and Reproductive Sciences, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America
Elissa S. Epel, Heather M. Burke
Department of Psychiatry and Health Psychology Program, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America
Jue Lin, Elizabeth H. Blackburn
Department of Biochemistry and Biophysics, University of California San Francisco (UCSF) School of Medicine, San Francisco, California, United States of America
Firdaus S. Dhabhar
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, United States of America
Yali Su
Kronos Science Laboratory, Phoenix, Arizona, United States of America

Corresponding Author

Email: owen.wolkowitz@ucsf.edu

Competing Interests

1. Drs. Elizabeth Blackburn, Elissa Epel and Jue Lin are co-founders of Telome Health, Inc., a diagnostics company related to telomere biology, and they own stock in the company. 2. Drs. Elizabeth Blackburn, Elissa Epel, Jue Lin, Owen Wolkowitz and Synthia Mellon, on behalf of the Regents of the University of California (who will be assignees of the patent), have applied for a patent covering the use of cell aging markers (including telomerase activity) as a biomarker of depression. This does not alter the authors' adherence to all the PLoS One policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: OMW SHM ESE FSD VIR HMB EHB. Performed the experiments: OMW SHM JL FSD YS VIR RR HMB EK JCN. Analyzed the data: OMW SHM ESE JL FSD RR HMB MC EHB. Contributed reagents/materials/analysis tools: SHM JL FSD YS EHB. Wrote the paper: OMW SHM ESE JL FSD YS VIR RR JCN EHB.