Assessing the Biological Significance of Gene Expression Signatures and Co-Expression Modules by Studying Their Network Properties

Pablo Minguez; Joaquin Dopazo

doi:10.1371/journal.pone.0017474

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Open Access

Peer-reviewed

Research Article

Assessing the Biological Significance of Gene Expression Signatures and Co-Expression Modules by Studying Their Network Properties

Pablo Minguez,

Current address: European Molecular Biology Laboratory, Heidelberg, Germany

Affiliation Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain
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Joaquin Dopazo

* E-mail: jdopazo@cipf.es

Affiliations Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain, CIBER de Enfermedades Raras (CIBERER), Valencia, Spain, Functional Genomics Node, (INB) at CIPF, Valencia, Spain
⨯

Assessing the Biological Significance of Gene Expression Signatures and Co-Expression Modules by Studying Their Network Properties

Pablo Minguez,
Joaquin Dopazo

Published: March 7, 2011
https://doi.org/10.1371/journal.pone.0017474

About the Authors

Pablo Minguez

Current address: European Molecular Biology Laboratory, Heidelberg, Germany

Affiliation Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain

Joaquin Dopazo

* E-mail: jdopazo@cipf.es

Affiliations Department of Bioinformatics and Genomics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain, CIBER de Enfermedades Raras (CIBERER), Valencia, Spain, Functional Genomics Node, (INB) at CIPF, Valencia, Spain

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Analyzed the data: PM. Wrote the paper: JD PM.

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Clustering coefficients
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Gene ontologies
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Interaction networks
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Microarrays
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Protein interaction networks
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Genetic networks
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Cancers and neoplasms
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Gene expression
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