About the Authors

Daniel W. Wheeler

Affiliation Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Andrew J. Thompson

Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

Federico Corletto

Affiliation Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Jill Reckless

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Justin C. T. Loke

Affiliation Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Nicolas Lapaque

Affiliation Department of Pathology, University of Cambridge, Cambridge, United Kingdom

Andrew J. Grant

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Pietro Mastroeni

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

David J. Grainger

Affiliation Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Claire L. Padgett

Affiliation Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

John A. O'Brien

Affiliation Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom

Nigel G. A. Miller

Affiliation Department of Pathology, University of Cambridge, Cambridge, United Kingdom

John Trowsdale

Affiliation Department of Pathology, University of Cambridge, Cambridge, United Kingdom

Sarah C. R. Lummis

Contributed equally to this work with: Sarah C. R. Lummis, David K. Menon, John S. Beech

sl120@mole.bio.cam.ac.uk

Affiliations Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom, Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom

David K. Menon

Contributed equally to this work with: Sarah C. R. Lummis, David K. Menon, John S. Beech

Affiliation Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

John S. Beech

Contributed equally to this work with: Sarah C. R. Lummis, David K. Menon, John S. Beech

Affiliation Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DW JT SL DM JB. Performed the experiments: DW AT FC JR JL NL AG PM DG CP JOB NM JT SL. Analyzed the data: DW AT FC JR JL NL AG PM DG CP NM JT SL. Wrote the paper: DW SL.