About the Authors

Yi-Ning Su

Contributed equally to this work with: Yi-Ning Su, Chia-Cheng Hung

Affiliations Graduate Institute of Clinical Genomics, National Taiwan University College of Medicine, Taipei, Taiwan, Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan

Chia-Cheng Hung

Contributed equally to this work with: Yi-Ning Su, Chia-Cheng Hung

Affiliations Graduate Institute of Clinical Genomics, National Taiwan University College of Medicine, Taipei, Taiwan, Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan

Shin-Yu Lin

Affiliations Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan

Fang-Yi Chen

Affiliation Department of Obstetrics and Gynecology, Taiwan Adventist Hospital, Taipei, Taiwan

Jimmy P. S. Chern

Affiliation Department of Family Medicine, Tao-Yuan General Hospital, Department of Health, Taoyuan, Taiwan

Chris Tsai

Affiliation Bionet Cooperation Inc., Taipei, Taiwan

Tai-Sheng Chang

Affiliation Bionet Cooperation Inc., Taipei, Taiwan

Chih-Chao Yang

Affiliation Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan

Hung Li

Affiliation Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan

Hong-Nerng Ho

Affiliation Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan

Chien-Nan Lee

leecn@ntu.edu.tw

Affiliation Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan

Competing Interests

CT and TSC were employed by a grant from the Bionet Cooperation (Taiwan) Inc. There are no products in development, marketed products or patents to declare. The authors also confirm that the involvement of the Bionet Cooperation (Taiwan) Inc. does not alter their adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YNS CCH CNL. Performed the experiments: YNS CCH SYL. Analyzed the data: CCH SYL JPSC. Contributed reagents/materials/analysis tools: FYC CT TSC CCY HNH. Wrote the manuscript: YNS CCH SYL. Laboratory design for the SMN1/SMN2 gene analyses of spinal muscular atrophy: HL.