PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression

Dan Wang; Yingjian Li; Chuanyue Wu; Youhua Liu

doi:10.1371/journal.pone.0017048

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Open Access

Peer-reviewed

Research Article

PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression

Dan Wang,

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Yingjian Li,

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Chuanyue Wu,

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Youhua Liu

* E-mail: liuy@upmc.edu

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯

PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression

Dan Wang,
Yingjian Li,
Chuanyue Wu,
Youhua Liu

Published: February 24, 2011
https://doi.org/10.1371/journal.pone.0017048

About the Authors

Dan Wang

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Yingjian Li

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Chuanyue Wu

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Youhua Liu

* E-mail: liuy@upmc.edu

Affiliation Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DW Y. Liu. Performed the experiments: DW Y. Li. Analyzed the data: DW CW Y. Liu. Contributed reagents/materials/analysis tools: CW. Wrote the paper: DW Y. Liu.

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Co-immunoprecipitation
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Immunoprecipitation
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Gene expression
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Transfection
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Transcription factors
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Protein expression
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Transcriptional control
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Focal adhesions
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