About the Authors

Liping Ren

Affiliations Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America, Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, University of Washington, Seattle, Washington, United States of America

Janel R. McLean

Affiliations Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America, Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, University of Washington, Seattle, Washington, United States of America

Tony R. Hazbun

Current address: Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, United States of America

Affiliations Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America, Department of Genome Sciences and Department of Medicine, University of Washington, Seattle, Washington, United States of America

Stanley Fields

Affiliations Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America, Department of Genome Sciences and Department of Medicine, University of Washington, Seattle, Washington, United States of America

Craig Vander Kooi

Affiliation Department of Molecular and Cellular Biochemistry and Center for Structural Biology, University of Kentucky, Lexington, Kentucky, United States of America

Melanie D. Ohi

Affiliation Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, University of Washington, Seattle, Washington, United States of America

Kathleen L. Gould

kathy.gould@vanderbilt.edu

Affiliations Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America, Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, University of Washington, Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TRH SF CVK MDO KLG. Performed the experiments: LR TRH CVK MDO. Analyzed the data: LR JRM TRH SF CVK MDO KLG. Contributed reagents/materials/analysis tools: LR TRH CVK. Wrote the paper: LR JRM SF CVK MDO KLG.