About the Authors

Xiaolan Hu

xiaolan.hu@pfizer.com

Affiliation Molecular Medicine, Pfizer Inc., Groton, Connecticut, United States of America

Eve Pickering

Affiliation Research Statistics, Pfizer Inc., Groton, Connecticut, United States of America

Yingxue Cathy Liu

Affiliation Clinical Statistics, Pfizer Inc., Shanghai, China

Stephanie Hall

Affiliation Molecular Medicine, Pfizer Inc., Groton, Connecticut, United States of America

Helene Fournier

Affiliation Genizon Biosciences Inc, Montreal, Canada

Elyse Katz

Affiliation Molecular Medicine, Pfizer Inc., Groton, Connecticut, United States of America

Bryan Dechairo

Current address: Medco Health Solutions, Bethesda, Maryland, United States of America

Affiliation Molecular Medicine, Pfizer Inc., Groton, Connecticut, United States of America

Sally John

Affiliation Molecular Medicine, Pfizer Inc., Groton, Connecticut, United States of America

Paul Van Eerdewegh

Affiliation Genizon Biosciences Inc, Montreal, Canada

Holly Soares

Current address: Bristol Myers Squibb Inc., Wallingford, Connecticut, United States of America

Affiliation Translational Medicine, Pfizer Inc., Groton, Connecticut, United States of America

the Alzheimer's Disease Neuroimaging Initiative

Information about membership in the Alzheimer's Disease Neuroimaging Initiative is available in the Acknowledgments.

Competing Interests

The authors are/were employees of Pfizer or Genizon Biosciences. This does not alter the authors' adherence to all the Plos One policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: XH HS. Performed the experiments: HF SH XH. Analyzed the data: XH EP YCL PVE. Contributed reagents/materials/analysis tools: BD EK SJ. Wrote the paper: XH EP.