About the Authors

Robert P. Young

roberty@adhb.govt.nz

Affiliations Department of Medicine, Auckland Hospital, Auckland, New Zealand, Synergenz Biosciences Ltd, Auckland, New Zealand

Raewyn J. Hopkins

Affiliation Department of Medicine, Auckland Hospital, Auckland, New Zealand

Chris F. Whittington

Affiliation Department of Medicine, Auckland Hospital, Auckland, New Zealand

Bryan A. Hay

Affiliation Department of Medicine, Auckland Hospital, Auckland, New Zealand

Michael J. Epton

Affiliation Department of Medicine, University of Otago, Christchurch, New Zealand

Gregory D. Gamble

Affiliation Department of Medicine, Auckland Hospital, Auckland, New Zealand

Competing Interests

Dr. Robert Young is a Scientific Advisor to Synergenz BioScience Ltd who assisted with funding this project. This does not alter the authors' adherence to all the PLos ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RPY RJH GDG. Performed the experiments: RPY BAH CFW. Analyzed the data: RPY RJH GDG. Contributed reagents/materials/analysis tools: RPY. Wrote the paper: RPY RJH CFW. Helped with recruitment of subjects: MJE.