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Research Article

Discovery of Novel Human Breast Cancer MicroRNAs from Deep Sequencing Data by Analysis of Pri-MicroRNA Secondary Structures

  • Seongho Ryu,

    Affiliations: Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, New York, United States of America, Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, New York, United States of America

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  • Natasha Joshi,

    Affiliations: Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, New York, United States of America, Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, New York, United States of America

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  • Kevin McDonnell,

    Affiliations: Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, New York, United States of America, Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, New York, United States of America

    Current address: Michigan State University, East Lansing, Michigan, United States of America

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  • Jongchan Woo,

    Affiliation: Laboratory of Plant Molecular Biology, Rockefeller University, New York, New York, United States of America

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  • Hyejin Choi,

    Affiliations: Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, New York, United States of America, Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, New York, United States of America

    X
  • Dingcheng Gao,

    Affiliations: Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, New York, United States of America, Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, New York, United States of America

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  • William R. McCombie,

    Affiliation: Cold Spring Harbor Laboratory, New York, New York, United States of America

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  • Vivek Mittal mail

    vim2010@med.cornell.edu

    Affiliations: Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, New York, United States of America, Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, New York, United States of America

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  • Published: February 08, 2011
  • DOI: 10.1371/journal.pone.0016403

About the Authors

Seongho Ryu, Natasha Joshi, Kevin McDonnell, Hyejin Choi, Dingcheng Gao, Vivek Mittal
Department of Cardiothoracic Surgery, Weill Cornell Medical College of Cornell University, New York, New York, United States of America
Seongho Ryu, Natasha Joshi, Kevin McDonnell, Hyejin Choi, Dingcheng Gao, Vivek Mittal
Department of Cell and Developmental Biology, Weill Cornell Medical College of Cornell University, New York, New York, United States of America
Jongchan Woo
Laboratory of Plant Molecular Biology, Rockefeller University, New York, New York, United States of America
William R. McCombie
Cold Spring Harbor Laboratory, New York, New York, United States of America

Corresponding Author

Email: vim2010@med.cornell.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SR NJ KM VM. Performed the experiments: SR NJ HC DG KM JW. Analyzed the data: SR NJ. Contributed reagents/materials/analysis tools: SR WRM. Wrote the paper: SR VM.