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Research Article

No Evidence for XMRV in German CFS and MS Patients with Fatigue Despite the Ability of the Virus to Infect Human Blood Cells In Vitro

  • Oliver Hohn,

    Affiliations: Centre for Biological Security 4, Robert Koch-Institute, Berlin, Germany, Centre for Retrovirology, Robert Koch-Institute, Berlin, Germany

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  • Kristin Strohschein,

    Affiliation: Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

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  • Alexander U. Brandt,

    Affiliation: NeuroCure Clinical Research Center (NCRC), Charité Universitätsmedizin Berlin, Berlin, Germany

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  • Sandra Seeher,

    Affiliation: Centre for Biological Security 4, Robert Koch-Institute, Berlin, Germany

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  • Sandra Klein,

    Affiliation: Centre for Biological Security 4, Robert Koch-Institute, Berlin, Germany

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  • Reinhard Kurth,

    Affiliation: Robert Koch-Institute, Berlin, Germany

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  • Friedemann Paul,

    Affiliation: NeuroCure Clinical Research Center (NCRC), Charité Universitätsmedizin Berlin, Berlin, Germany

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  • Christian Meisel,

    Affiliation: Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

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  • Carmen Scheibenbogen equal contributor,

    equal contributor Contributed equally to this work with: Carmen Scheibenbogen, Norbert Bannert

    Affiliation: Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

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  • Norbert Bannert equal contributor mail

    equal contributor Contributed equally to this work with: Carmen Scheibenbogen, Norbert Bannert

    bannertn@rki.de

    Affiliations: Centre for Biological Security 4, Robert Koch-Institute, Berlin, Germany, Centre for Retrovirology, Robert Koch-Institute, Berlin, Germany

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  • Published: December 22, 2010
  • DOI: 10.1371/journal.pone.0015632

About the Authors

Oliver Hohn, Sandra Seeher, Sandra Klein, Norbert Bannert
Centre for Biological Security 4, Robert Koch-Institute, Berlin, Germany
Kristin Strohschein, Christian Meisel, Carmen Scheibenbogen
Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany
Alexander U. Brandt, Friedemann Paul
NeuroCure Clinical Research Center (NCRC), Charité Universitätsmedizin Berlin, Berlin, Germany
Reinhard Kurth
Robert Koch-Institute, Berlin, Germany
Oliver Hohn, Norbert Bannert
Centre for Retrovirology, Robert Koch-Institute, Berlin, Germany

Corresponding Author

Email: bannertn@rki.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NB OH CS FP AUB RK. Performed the experiments: OH SS SK KS AUB. Analyzed the data: NB OH KS AUB CS FP. Contributed reagents/materials/analysis tools: CM AUB KS. Wrote the paper: OH NB.