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Research Article

The Use of Gamma-H2AX as a Biodosimeter for Total-Body Radiation Exposure in Non-Human Primates

  • Christophe E. Redon mail,

    redonc@mail.nih.gov

    Affiliation: Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Asako J. Nakamura,

    Affiliation: Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Ksenia Gouliaeva,

    Affiliation: Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Arifur Rahman,

    Affiliation: Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, Maryland, United States of America

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  • William F. Blakely,

    Affiliation: Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, Maryland, United States of America

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  • William M. Bonner

    Affiliation: Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: November 23, 2010
  • DOI: 10.1371/journal.pone.0015544

About the Authors

Christophe E. Redon, Asako J. Nakamura, Ksenia Gouliaeva, William M. Bonner
Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Arifur Rahman, William F. Blakely
Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, Maryland, United States of America

Corresponding Author

Email: redonc@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CR AN AR WFB WMB. Performed the experiments: CR AN AR KG WFB. Analyzed the data: CR AN WFB WMB. Contributed reagents/materials/analysis tools: CR AN AR KG WFB WMB. Wrote the paper: CR AN WFB WMB. Reviewed the manuscript: KG AR.