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Research Article

Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

  • Nicholas P. Whitehead mail,

    npwhite@u.washington.edu

    Affiliations: Discipline of Physiology, Bosch Institute, The University of Sydney, Sydney, New South Wales, Australia, Department of Physiology & Biophysics, University of Washington, Seattle, Washington, United States of America

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  • Ella W. Yeung,

    Affiliation: Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, Special Administrative Region, People's Republic of China

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  • Stanley C. Froehner,

    Affiliation: Department of Physiology & Biophysics, University of Washington, Seattle, Washington, United States of America

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  • David G. Allen

    Affiliation: Discipline of Physiology, Bosch Institute, The University of Sydney, Sydney, New South Wales, Australia

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  • Published: December 20, 2010
  • DOI: 10.1371/journal.pone.0015354

About the Authors

Nicholas P. Whitehead, David G. Allen
Discipline of Physiology, Bosch Institute, The University of Sydney, Sydney, New South Wales, Australia
Nicholas P. Whitehead, Stanley C. Froehner
Department of Physiology & Biophysics, University of Washington, Seattle, Washington, United States of America
Ella W. Yeung
Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, Special Administrative Region, People's Republic of China

Corresponding Author

Email: npwhite@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NPW DGA. Performed the experiments: NPW EWY. Analyzed the data: NPW EWY. Contributed reagents/materials/analysis tools: DGA SCF. Wrote the paper: NPW EWY SCF DGA.