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Research Article

A Porcine Adenovirus with Low Human Seroprevalence Is a Promising Alternative Vaccine Vector to Human Adenovirus 5 in an H5N1 Virus Disease Model

  • Ami Patel,

    Affiliations: National Microbiology Laboratory, Public Health Agency of Canada, Canadian Science Centre for Human and Animal Health, Winnipeg, Canada, Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada

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  • Suresh Tikoo,

    Affiliation: Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, Canada

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  • Gary Kobinger mail

    gary_kobinger@phac-aspc.gc.ca

    Affiliations: National Microbiology Laboratory, Public Health Agency of Canada, Canadian Science Centre for Human and Animal Health, Winnipeg, Canada, Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada

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  • Published: December 16, 2010
  • DOI: 10.1371/journal.pone.0015301

About the Authors

Ami Patel, Gary Kobinger
National Microbiology Laboratory, Public Health Agency of Canada, Canadian Science Centre for Human and Animal Health, Winnipeg, Canada
Ami Patel, Gary Kobinger
Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada
Suresh Tikoo
Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, Canada

Corresponding Author

Email: gary_kobinger@phac-aspc.gc.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GK AP. Performed the experiments: GK AP. Analyzed the data: GK AP. Contributed reagents/materials/analysis tools: GK ST. Wrote the paper: GK AP.