About the Authors

Andrea L. Conroy

Affiliation Sandra A. Rotman Laboratories, McLaughlin-Rotman Centre for Global Health, University Health Network-Toronto General Hospital, University of Toronto, Toronto, Canada

Happy Phiri

Affiliation Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi

Michael Hawkes

Affiliation Sandra A. Rotman Laboratories, McLaughlin-Rotman Centre for Global Health, University Health Network-Toronto General Hospital, University of Toronto, Toronto, Canada

Simon Glover

Affiliation College of Medicine, University of Malawi, Blantyre, Malawi

Mac Mallewa

Affiliations Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi, School of Tropical Medicine, University of Liverpool, Liverpool, United Kingdom

Karl B. Seydel

Affiliations Blantyre Malaria Project, College of Medicine, University of Malawi, Blantyre, Malawi, Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America

Terrie E. Taylor

Affiliations Blantyre Malaria Project, College of Medicine, University of Malawi, Blantyre, Malawi, Department of Internal Medicine, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, United States of America

Malcolm E. Molyneux

Affiliations Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi, College of Medicine, University of Malawi, Blantyre, Malawi, School of Tropical Medicine, University of Liverpool, Liverpool, United Kingdom

Kevin C. Kain

kevin.kain@uhn.on.ca

Affiliations Sandra A. Rotman Laboratories, McLaughlin-Rotman Centre for Global Health, University Health Network-Toronto General Hospital, University of Toronto, Toronto, Canada, Tropical Disease Unit, Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, Canada

Competing Interests

KCK and AC are listed as inventors on a patent owned by the University Health Network related to host biomarkers of malaria (date of filing: August 8, 2010; Provisional Patent Serial Number: 61/371,401). This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: ALC TET MEM KCK. Performed the experiments: ALC. Analyzed the data: ALC MH. Contributed reagents/materials/analysis tools: SG KBS MM TET MEM KCK. Wrote the paper: ALC KCK. Contributed to revisions of the text: ALC HP MH SG MM KBS TET MEM KCK. Organized collection of clinical samples and clinical data: HP SG KBS MM TET MEM.