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Research Article

Altered Effective Connectivity Network of the Amygdala in Social Anxiety Disorder: A Resting-State fMRI Study

  • Wei Liao equal contributor,

    equal contributor Contributed equally to this work with: Wei Liao, Changjian Qiu

    Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, People's Republic of China

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  • Changjian Qiu equal contributor,

    equal contributor Contributed equally to this work with: Wei Liao, Changjian Qiu

    Affiliation: Mental Health Center, West China Hospital of Sichuan University, Chengdu, People's Republic of China

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  • Claudio Gentili,

    Affiliation: Unit of Clinical Psychology, AUO Pisa, Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Pisa, Italy

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  • Martin Walter,

    Affiliation: Clinical Affective Neuroimaging Laboratory, Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany

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  • Zhengyong Pan,

    Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, People's Republic of China

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  • Jurong Ding,

    Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, People's Republic of China

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  • Wei Zhang,

    Affiliation: Mental Health Center, West China Hospital of Sichuan University, Chengdu, People's Republic of China

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  • Qiyong Gong mail,

    chenhf@uestc.edu.cn (HC); qygong05@126.com (QG)

    Affiliation: Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, West China School of Medicine, Chengdu, People's Republic of China

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  • Huafu Chen mail

    chenhf@uestc.edu.cn (HC); qygong05@126.com (QG)

    Affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, People's Republic of China

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  • Published: December 22, 2010
  • DOI: 10.1371/journal.pone.0015238

About the Authors

Wei Liao, Zhengyong Pan, Jurong Ding, Huafu Chen
Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, People's Republic of China
Changjian Qiu, Wei Zhang
Mental Health Center, West China Hospital of Sichuan University, Chengdu, People's Republic of China
Claudio Gentili
Unit of Clinical Psychology, AUO Pisa, Department of Psychiatry, Neurobiology, Pharmacology and Biotechnologies, University of Pisa, Pisa, Italy
Martin Walter
Clinical Affective Neuroimaging Laboratory, Department of Psychiatry, Otto von Guericke University, Magdeburg, Germany
Qiyong Gong
Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, West China School of Medicine, Chengdu, People's Republic of China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HC WZ QG. Performed the experiments: HC WZ QG. Analyzed the data: WL ZP JD HC. Contributed reagents/materials/analysis tools: WL CQ WZ HC QG. Wrote the paper: WL CG MW.