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Research Article

Partial Netrin-1 Deficiency Aggravates Acute Kidney Injury

  • Almut Grenz mail,

    Almut.Grenz@ucdenver.edu (AG); holger.eltzschig@ucdenver.edu (HKE)

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Julee H. Dalton,

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Jessica D. Bauerle,

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Alexander Badulak,

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Douglas Ridyard,

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Aneta Gandjeva,

    Affiliation: Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Carol M. Aherne,

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Kelley S. Brodsky,

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

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  • Jae-Hwan Kim,

    Affiliations: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America, Department of Anesthesiology, Korea University College of Medicine, Seoul, Republic of Korea

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  • Rubin M. Tuder,

    Affiliation: Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

    X
  • Holger K. Eltzschig mail

    Almut.Grenz@ucdenver.edu (AG); holger.eltzschig@ucdenver.edu (HKE)

    Affiliation: Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America

    X
  • Published: May 19, 2011
  • DOI: 10.1371/journal.pone.0014812

About the Authors

Almut Grenz, Julee H. Dalton, Jessica D. Bauerle, Alexander Badulak, Douglas Ridyard, Carol M. Aherne, Kelley S. Brodsky, Jae-Hwan Kim, Holger K. Eltzschig
Mucosal Inflammation Program, Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
Aneta Gandjeva, Rubin M. Tuder
Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
Jae-Hwan Kim
Department of Anesthesiology, Korea University College of Medicine, Seoul, Republic of Korea

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AG HKE. Performed the experiments: AG JHD JDB AB DR AG CMA KSB JHK RMT. Analyzed the data: AG JHD JDB AB DR CMA KSB JHK RMT. Contributed reagents/materials/analysis tools: AB DR RMT. Wrote the paper: AG HKE.