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Research Article

Autoantibodies to Endothelial Cell Surface ATP Synthase, the Endogenous Receptor for Hsp60, Might Play a Pathogenic Role in Vasculatides

  • Jean-Eric Alard,

    Affiliation: EA2216 “Immunology and Pathology” and IFR 148 ScInBioS, Université de Brest and Université Européenne de Bretagne, Brest, France

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  • Sophie Hillion,

    Affiliation: EA2216 “Immunology and Pathology” and IFR 148 ScInBioS, Université de Brest and Université Européenne de Bretagne, Brest, France

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  • Loïc Guillevin,

    Affiliation: Department of Internal Medicine, Hôpital Cochin, Paris, France

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  • Alain Saraux,

    Affiliations: EA2216 “Immunology and Pathology” and IFR 148 ScInBioS, Université de Brest and Université Européenne de Bretagne, Brest, France, Centre Hospitalier Universitaire, Brest, France

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  • Jacques-Olivier Pers,

    Affiliations: EA2216 “Immunology and Pathology” and IFR 148 ScInBioS, Université de Brest and Université Européenne de Bretagne, Brest, France, Centre Hospitalier Universitaire, Brest, France

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  • Pierre Youinou mail,

    youinou@univ-brest.fr

    Affiliations: EA2216 “Immunology and Pathology” and IFR 148 ScInBioS, Université de Brest and Université Européenne de Bretagne, Brest, France, Centre Hospitalier Universitaire, Brest, France

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  • Christophe Jamin

    Affiliations: EA2216 “Immunology and Pathology” and IFR 148 ScInBioS, Université de Brest and Université Européenne de Bretagne, Brest, France, Centre Hospitalier Universitaire, Brest, France

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  • Published: February 07, 2011
  • DOI: 10.1371/journal.pone.0014654

About the Authors

Jean-Eric Alard, Sophie Hillion, Alain Saraux, Jacques-Olivier Pers, Pierre Youinou, Christophe Jamin
EA2216 “Immunology and Pathology” and IFR 148 ScInBioS, Université de Brest and Université Européenne de Bretagne, Brest, France
Loïc Guillevin
Department of Internal Medicine, Hôpital Cochin, Paris, France
Alain Saraux, Jacques-Olivier Pers, Pierre Youinou, Christophe Jamin
Centre Hospitalier Universitaire, Brest, France

Corresponding Author

Email: youinou@univ-brest.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JEA PY CJ. Performed the experiments: JEA. Analyzed the data: JEA SH LG AS JOP CJ. Contributed reagents/materials/analysis tools: JEA SH LG AS JOP. Wrote the paper: PY CJ.