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Research Article

Effects of an Alpha-4 Integrin Inhibitor on Restenosis in a New Porcine Model Combining Endothelial Denudation and Stent Placement

  • Anne Braun equal contributor mail,

    equal contributor Contributed equally to this work with: Anne Braun, Lilibeth Dofiles

    bostonegles@yahoo.com

    Affiliation: Charles River Laboratories, Preclinical Services Massachusetts, Shrewsbury, Massachusetts, United States of America

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  • Lilibeth Dofiles equal contributor,

    equal contributor Contributed equally to this work with: Anne Braun, Lilibeth Dofiles

    Affiliation: Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

    X
  • Serge Rousselle,

    Affiliation: Alizee Pathology, LLC, Thurmont, Maryland, United States of America

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  • Luis Guerrero,

    Affiliation: Charles River Laboratories, Preclinical Services Massachusetts, Shrewsbury, Massachusetts, United States of America

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  • Jane Gunther,

    Affiliation: Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

    X
  • Ted Yednock,

    Affiliation: Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

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  • Alain Stricker-Krongrad,

    Affiliation: Charles River Laboratories, Preclinical Services Massachusetts, Shrewsbury, Massachusetts, United States of America

    X
  • Elizabeth Messersmith

    Affiliation: Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America

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  • Published: December 13, 2010
  • DOI: 10.1371/journal.pone.0014314

About the Authors

Anne Braun, Luis Guerrero, Alain Stricker-Krongrad
Charles River Laboratories, Preclinical Services Massachusetts, Shrewsbury, Massachusetts, United States of America
Lilibeth Dofiles, Jane Gunther, Ted Yednock, Elizabeth Messersmith
Elan Pharmaceuticals, Inc., South San Francisco, California, United States of America
Serge Rousselle
Alizee Pathology, LLC, Thurmont, Maryland, United States of America

Corresponding Author

Email: bostonegles@yahoo.com

Competing Interests

Lilibeth Dofiles, Jane Gunther, Ted Yednock and Elizabeth Messersmith are employees of Elan Pharmaceuticals, the funder of this work. While these authors are employed by Elan Pharmaceuticals, it does not alter their adherance to all of the PLoS ONE policies on sharing data and materials. While Serge Rousselle is an employee of Alizee Pharmacology LLC, it does not alter his adherance to all of the PLoS ONE policies on sharing data and materials. While Anne Braun, Luis Guerrero and Alain Stricker-Krongrad are employees of Charles River Laboratories, it does not alter their adherance to all of the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AB LD SR JG TY ASK EM. Performed the experiments: AB SR LG. Analyzed the data: AB LD SR. Contributed reagents/materials/analysis tools: LD LG JG. Wrote the paper: AB LD ASK.