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Research Article

Activation of Protein Serine/Threonine Phosphatase PP2Cα Efficiently Prevents Liver Fibrosis

  • Lirui Wang equal contributor,

    equal contributor Contributed equally to this work with: Lirui Wang, Xu Wang

    Affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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  • Xu Wang equal contributor,

    equal contributor Contributed equally to this work with: Lirui Wang, Xu Wang

    Affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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  • Jing Chen,

    Affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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  • Zhengyi Yang,

    Affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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  • Liang Yu,

    Affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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  • Lihong Hu mail,

    xshen@mail.shcnc.ac.cn (XS); simmhlh@mail.shcnc.ac.cn (LH)

    Affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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  • Xu Shen mail

    xshen@mail.shcnc.ac.cn (XS); simmhlh@mail.shcnc.ac.cn (LH)

    Affiliations: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, E-Institutes of Shanghai Municipal Education Commission, Shanghai Jiaotong University School of Medicine, Shanghai, China

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  • Published: December 06, 2010
  • DOI: 10.1371/journal.pone.0014230

About the Authors

Lirui Wang, Xu Wang, Jing Chen, Zhengyi Yang, Liang Yu, Lihong Hu, Xu Shen
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
Xu Shen
E-Institutes of Shanghai Municipal Education Commission, Shanghai Jiaotong University School of Medicine, Shanghai, China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LW XW JC LH XS. Performed the experiments: LW XW LY. Analyzed the data: LW XW JC LH XS. Contributed reagents/materials/analysis tools: ZY LH. Wrote the paper: LW XW XS.