About the Authors
- Hayley C. Whitaker
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* E-mail: Hayley.Whitaker@cancer.org.uk
Affiliation Uro-Oncology Research Group, CRUK Cambridge Research Institute, Cambridge, United Kingdom
- Zsofia Kote-Jarai
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Contributed equally to this work with: Zsofia Kote-Jarai, Helen Ross-Adams
Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Helen Ross-Adams
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Contributed equally to this work with: Zsofia Kote-Jarai, Helen Ross-Adams
Affiliation Uro-Oncology Research Group, CRUK Cambridge Research Institute, Cambridge, United Kingdom
- Anne Y. Warren
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Affiliation Department of Pathology, Addenbrookes Hospital, Cambridge, United Kingdom
- Johanna Burge
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Affiliation Uro-Oncology Research Group, CRUK Cambridge Research Institute, Cambridge, United Kingdom
- Anne George
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Affiliation Uro-Oncology Research Group, CRUK Cambridge Research Institute, Cambridge, United Kingdom
- Elizabeth Bancroft
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Sameer Jhavar
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Daniel Leongamornlert
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Malgorzata Tymrakiewicz
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Edward Saunders
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Elizabeth Page
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Anita Mitra
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Gillian Mitchell
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Affiliation Peter Maccallum Cancer Centre, Victoria, Australia
- Geoffrey J. Lindeman
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Affiliation The Royal Melbourne Hospital and The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
- D. Gareth Evans
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Affiliation Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom
- Ignacio Blanco
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Affiliation Catalonian Institute of Oncology, L'Hospitalet, Barcelona, Spain
- Catherine Mercer
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Affiliation Wessex Clinical Genetics Service, The Princess Anne Hospital, Southampton, United Kingdom
- Wendy S. Rubinstein
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Affiliation NorthShore University Health System, Evanston, Illinois, United States of America
- Virginia Clowes
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Affiliation Department of Clinical Genetics, Addenbrookes Hospital, Cambridge, United Kingdom
- Fiona Douglas
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Affiliation Institute of Human Genetics, Newcastle-Upon-Tyne, United Kingdom
- Shirley Hodgson
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Affiliation St George's, University of London, London, United Kingdom
- Lisa Walker
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Affiliation Oxford Regional Genetics Centre, Churchill Hospital, Oxford, United Kingdom
- Alan Donaldson
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Affiliation St Michael's Hospital, Bristol, United Kingdom
- Louise Izatt
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Affiliation Guy's Hospital, London, United Kingdom
- Huw Dorkins
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Affiliation Kennedy Galton Centre, Northwick Park Hospital, Harrow, Middlesex, United Kingdom
- Alison Male
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Affiliation Institute of Child Health, London, United Kingdom
- Kathy Tucker
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Affiliation Prince of Wales Hospital, Sydney, New South Wales, Australia
- Alan Stapleton
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Affiliation Repatriation General Hospital, Adelaide, Australia
- Jimmy Lam
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Affiliation Repatriation General Hospital, Adelaide, Australia
- Judy Kirk
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Affiliation Familial Cancer Service, Westmead Hospital, Westmead, New South Wales, Australia
- Hans Lilja
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Affiliation Departments of Clinical Laboratories, Surgery, Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
- Douglas Easton
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Affiliation Cancer Research UK Genetic Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom
- The IMPACT Study Steering Committee
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¶List of The IMPACT Study Steering Committee available on request.
- The IMPACT Study Collaborators
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¶List of The IMPACT Study Collaborators available on request.
- UK GPCS Collaborators
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¶List of UK GPCS Collaborators available on request.
- Colin Cooper
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- Rosalind Eeles
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Affiliations The Institute of Cancer Research, Sutton, Surrey, United Kingdom, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
- David E. Neal
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Affiliation Uro-Oncology Research Group, CRUK Cambridge Research Institute, Cambridge, United Kingdom
Competing Interests
Dr. Hans Lilja holds patents for free PSA and hK2 assays. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: HCW ZKJ SJ DL MT ES AM GM GJL DGE IB CM WSR VC FD SH LW AD LI HD AM KT AS JL JK TISC TISC UBC CC RAE DN. Performed the experiments: HCW ZKJ HRA AYW JB AG SJ DL MT ES EP AM GM GJL DGE IB CM WSR VC FD SH LW AD LI HD AM KT AS JL TISC TISC UBC CC. Analyzed the data: HCW ZKJ HRA AYW JB AG EB EP HL DFE RAE DN. Contributed reagents/materials/analysis tools: HCW ZKJ HRA AYW JB AG EB SJ DL MT ES EP AM GM GJL DGE IB CM WSR VC FD SH LW AD LI HD AM KT AS JL JK HL DFE TISC TISC UBC CC RAE DN. Wrote the paper: HCW ZKJ EB WSR DFE RAE DN.