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Research Article

Genipin-Induced Inhibition of Uncoupling Protein-2 Sensitizes Drug-Resistant Cancer Cells to Cytotoxic Agents

  • Ryan J. Mailloux,

    Affiliation: Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada

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  • Cyril Nii-Klu Adjeitey,

    Affiliation: Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada

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  • Mary-Ellen Harper mail

    mharper@uottawa.ca

    Affiliation: Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada

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  • Published: October 13, 2010
  • DOI: 10.1371/journal.pone.0013289

About the Authors

Ryan J. Mailloux, Cyril Nii-Klu Adjeitey, Mary-Ellen Harper
Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada

Corresponding Author

Email: mharper@uottawa.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RJM MEH. Performed the experiments: RJM CNKA. Analyzed the data: RJM CNKA MEH. Contributed reagents/materials/analysis tools: MEH. Wrote the paper: RJM MEH.